Cargando…
Anti-fibrotic action of pirfenidone in Dupuytren’s disease-derived fibroblasts
BACKGROUND: Dupuytren’s disease (DD) is a complex fibro-proliferative disorder of the hand that is often progressive and eventually can cause contractures of the affected fingers. Transforming growth factor beta (TGF-β(1)) has been implicated as a key stimulator of myofibroblast activity and fascial...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106805/ https://www.ncbi.nlm.nih.gov/pubmed/27835939 http://dx.doi.org/10.1186/s12891-016-1326-y |