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Rac Attack: Modulation of the Small GTPase Rac in Inflammatory Bowel Disease and Thiopurine Therapy

The incidence and prevalence of inflammatory bowel disease (IBD) are increasing. Although the etiology of IBD is unknown, it is thought that genetically susceptible individuals display an inappropriate inflammatory response to commensal microbes, resulting in intestinal tissue damage. Key proteins i...

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Detalles Bibliográficos
Autores principales: Seinen, Margien L., van Nieuw Amerongen, Geerten P., de Boer, Nanne K. H., van Bodegraven, Adriaan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107185/
https://www.ncbi.nlm.nih.gov/pubmed/27604084
http://dx.doi.org/10.1007/s40291-016-0232-1