Long-Term Safety Follow-Up of Subjects Previously Treated with Non-Replicating Retroviral Vector-Based Gene Therapies

OBJECTIVE: Our objective was to evaluate the life-long safety profile of gene therapy using retroviral (non-replicating) vectors (nRCR), or cell products in 127 subjects with hemophilia, human immunodeficiency virus (HIV), or cancer, previously treated with such gene therapy. METHODS: We assessed th...

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Detalles Bibliográficos
Autores principales: Mohanlal, Ramon, Qiu, Yuhong, Zheng, Ming, Mirkou, Asmae, Sridharan, Kanaka, Keir, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107205/
https://www.ncbi.nlm.nih.gov/pubmed/27435702
http://dx.doi.org/10.1007/s40291-016-0229-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107205/
https://www.ncbi.nlm.nih.gov/pubmed/27435702
http://dx.doi.org/10.1007/s40291-016-0229-9

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