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Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania

Background. Elevated blood pressure has been reported among treatment naïve HIV-infected patients. We investigated prevalence of hypertension and its associated risk factors in a HAART naïve HIV-infected population in Dar es Salaam, Tanzania. Methods. A cross-sectional analysis was conducted among H...

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Autores principales: Njelekela, Marina, Muhihi, Alfa, Aveika, Akum, Spiegelman, Donna, Hawkins, Claudia, Armstrong, Catharina, Liu, Enju, Okuma, James, Chalamila, Guerino, Kaaya, Sylvia, Mugusi, Ferdinand, Fawzi, Wafaie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107235/
https://www.ncbi.nlm.nih.gov/pubmed/27872756
http://dx.doi.org/10.1155/2016/5958382
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author Njelekela, Marina
Muhihi, Alfa
Aveika, Akum
Spiegelman, Donna
Hawkins, Claudia
Armstrong, Catharina
Liu, Enju
Okuma, James
Chalamila, Guerino
Kaaya, Sylvia
Mugusi, Ferdinand
Fawzi, Wafaie
author_facet Njelekela, Marina
Muhihi, Alfa
Aveika, Akum
Spiegelman, Donna
Hawkins, Claudia
Armstrong, Catharina
Liu, Enju
Okuma, James
Chalamila, Guerino
Kaaya, Sylvia
Mugusi, Ferdinand
Fawzi, Wafaie
author_sort Njelekela, Marina
collection PubMed
description Background. Elevated blood pressure has been reported among treatment naïve HIV-infected patients. We investigated prevalence of hypertension and its associated risk factors in a HAART naïve HIV-infected population in Dar es Salaam, Tanzania. Methods. A cross-sectional analysis was conducted among HAART naïve HIV-infected patients. Hypertension was defined as systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg. Overweight and obesity were defined as body mass index (BMI) between 25.0–29.9 kg/m(2) and ≥30 kg/m(2), respectively. We used relative risks to examine factors associated with hypertension. Results. Prevalence of hypertension was found to be 12.5%. After adjusting for possible confounders, risk of hypertension was 10% more in male than female patients. Patients aged ≥50 years had more than 2-fold increased risk for hypertension compared to 30–39-years-old patients. Overweight and obesity were associated with 51% and 94% increased risk for hypertension compared to normal weight patients. Low CD4+ T-cell count, advanced WHO clinical disease stage, and history of TB were associated with 10%, 42%, and 14% decreased risk for hypertension. Conclusions. Older age, male gender, and overweight/obesity were associated with hypertension. Immune suppression and history of TB were associated with lower risk for hypertension. HIV treatment programs should screen and manage hypertension even in HAART naïve individuals.
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spelling pubmed-51072352016-11-21 Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania Njelekela, Marina Muhihi, Alfa Aveika, Akum Spiegelman, Donna Hawkins, Claudia Armstrong, Catharina Liu, Enju Okuma, James Chalamila, Guerino Kaaya, Sylvia Mugusi, Ferdinand Fawzi, Wafaie Int J Hypertens Research Article Background. Elevated blood pressure has been reported among treatment naïve HIV-infected patients. We investigated prevalence of hypertension and its associated risk factors in a HAART naïve HIV-infected population in Dar es Salaam, Tanzania. Methods. A cross-sectional analysis was conducted among HAART naïve HIV-infected patients. Hypertension was defined as systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg. Overweight and obesity were defined as body mass index (BMI) between 25.0–29.9 kg/m(2) and ≥30 kg/m(2), respectively. We used relative risks to examine factors associated with hypertension. Results. Prevalence of hypertension was found to be 12.5%. After adjusting for possible confounders, risk of hypertension was 10% more in male than female patients. Patients aged ≥50 years had more than 2-fold increased risk for hypertension compared to 30–39-years-old patients. Overweight and obesity were associated with 51% and 94% increased risk for hypertension compared to normal weight patients. Low CD4+ T-cell count, advanced WHO clinical disease stage, and history of TB were associated with 10%, 42%, and 14% decreased risk for hypertension. Conclusions. Older age, male gender, and overweight/obesity were associated with hypertension. Immune suppression and history of TB were associated with lower risk for hypertension. HIV treatment programs should screen and manage hypertension even in HAART naïve individuals. Hindawi Publishing Corporation 2016 2016-10-30 /pmc/articles/PMC5107235/ /pubmed/27872756 http://dx.doi.org/10.1155/2016/5958382 Text en Copyright © 2016 Marina Njelekela et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Njelekela, Marina
Muhihi, Alfa
Aveika, Akum
Spiegelman, Donna
Hawkins, Claudia
Armstrong, Catharina
Liu, Enju
Okuma, James
Chalamila, Guerino
Kaaya, Sylvia
Mugusi, Ferdinand
Fawzi, Wafaie
Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania
title Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania
title_full Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania
title_fullStr Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania
title_full_unstemmed Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania
title_short Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania
title_sort prevalence of hypertension and its associated risk factors among 34,111 haart naïve hiv-infected adults in dar es salaam, tanzania
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107235/
https://www.ncbi.nlm.nih.gov/pubmed/27872756
http://dx.doi.org/10.1155/2016/5958382
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