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Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients

OBJECTIVE: To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE. METHODS: This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epil...

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Autores principales: Caglar, Veli, Alp, Selen I., Demir, Berrin T., Sener, Umit, Ozen, Oguz A., Alp, Recep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Riyadh : Armed Forces Hospital 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107269/
https://www.ncbi.nlm.nih.gov/pubmed/27094525
http://dx.doi.org/10.17712/nsj.2016.2.20150783
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author Caglar, Veli
Alp, Selen I.
Demir, Berrin T.
Sener, Umit
Ozen, Oguz A.
Alp, Recep
author_facet Caglar, Veli
Alp, Selen I.
Demir, Berrin T.
Sener, Umit
Ozen, Oguz A.
Alp, Recep
author_sort Caglar, Veli
collection PubMed
description OBJECTIVE: To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE. METHODS: This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epileptic syndrome diagnosis was based on International League Against Epilepsy criteria, and this study was conducted on the MRIs of 25 epilepsy patients and 25 control subjects. We classified the patients according to their duration of epilepsy <10 and ≥10 years. The projection area length (PAL) of the CC was also estimated. Total brain volumes (TBV) were measured on CT images. RESULTS: The mean values of TBV for patients with TLE and the control group were not statistically different, but the CC PAL values were statistically different. The mean CC PAL values of under and over 25 years of age in patients with TLE were statistically different. The mean values of TBV of under and over 10 years duration of TLE were small statistically, but the CC PAL values were statistically different. CONCLUSION: The results indicate a clear influence of TLE on the structure of the CC rather than TBV.
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spelling pubmed-51072692016-11-17 Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients Caglar, Veli Alp, Selen I. Demir, Berrin T. Sener, Umit Ozen, Oguz A. Alp, Recep Neurosciences (Riyadh) Original Article OBJECTIVE: To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE. METHODS: This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epileptic syndrome diagnosis was based on International League Against Epilepsy criteria, and this study was conducted on the MRIs of 25 epilepsy patients and 25 control subjects. We classified the patients according to their duration of epilepsy <10 and ≥10 years. The projection area length (PAL) of the CC was also estimated. Total brain volumes (TBV) were measured on CT images. RESULTS: The mean values of TBV for patients with TLE and the control group were not statistically different, but the CC PAL values were statistically different. The mean CC PAL values of under and over 25 years of age in patients with TLE were statistically different. The mean values of TBV of under and over 10 years duration of TLE were small statistically, but the CC PAL values were statistically different. CONCLUSION: The results indicate a clear influence of TLE on the structure of the CC rather than TBV. Riyadh : Armed Forces Hospital 2016-04 /pmc/articles/PMC5107269/ /pubmed/27094525 http://dx.doi.org/10.17712/nsj.2016.2.20150783 Text en Copyright: © Neurosciences https://creativecommons.org/licenses/by-nc-sa/3.0/Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.
spellingShingle Original Article
Caglar, Veli
Alp, Selen I.
Demir, Berrin T.
Sener, Umit
Ozen, Oguz A.
Alp, Recep
Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
title Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
title_full Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
title_fullStr Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
title_full_unstemmed Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
title_short Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
title_sort planimetry investigation of the corpus callosum in temporal lobe epilepsy patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107269/
https://www.ncbi.nlm.nih.gov/pubmed/27094525
http://dx.doi.org/10.17712/nsj.2016.2.20150783
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