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Carbon monoxide contributes to the constipating effects of granisetron in rat colon

AIM: To investigate the mechanisms underlying the potential contribution of the heme oxygenase/carbon monoxide (HO/CO) pathway in the constipating effects of granisetron. METHODS: For in vivo studies, gastrointestinal motility was evaluated in male rats acutely treated with granisetron [25, 50, 75 μ...

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Detalles Bibliográficos
Autores principales:	Nacci, Carmela, Fanelli, Margherita, Potenza, Maria Assunta, Leo, Valentina, Montagnani, Monica, De Salvia, Maria Antonietta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2016
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107697/ https://www.ncbi.nlm.nih.gov/pubmed/27895421 http://dx.doi.org/10.3748/wjg.v22.i42.9333

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