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Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma

Polymorphisms in the CAV1/2 genes that encode signature proteins of caveolae are associated with glaucoma, the second leading cause of blindness worldwide, and with its major risk factor, intraocular pressure (IOP). We hypothesized that caveolin-1 (Cav-1) participates in IOP maintenance via modulati...

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Detalles Bibliográficos
Autores principales: Elliott, Michael H., Ashpole, Nicole E., Gu, Xiaowu, Herrnberger, Leonie, McClellan, Mark E., Griffith, Gina L., Reagan, Alaina M., Boyce, Timothy M., Tanito, Masaki, Tamm, Ernst R., Stamer, W. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107904/
https://www.ncbi.nlm.nih.gov/pubmed/27841369
http://dx.doi.org/10.1038/srep37127