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Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer

Phase III clinical trials evaluating bevacizumab (an antibody to the angiogenic ligand, VEGF-A) in breast cancer have found improved responses in the presurgical neoadjuvant setting but no benefits in the postsurgical adjuvant setting. The objective of this study was to evaluate alternative antiangi...

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Detalles Bibliográficos
Autores principales: Wu, Florence T. H., Paez-Ribes, Marta, Xu, Ping, Man, Shan, Bogdanovic, Elena, Thurston, Gavin, Kerbel, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107907/
https://www.ncbi.nlm.nih.gov/pubmed/27841282
http://dx.doi.org/10.1038/srep36694