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Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction
A 32‐year‐old man presented with palpitation. He was diagnosed with pulmonary sarcoidosis by lung biopsy. The electrocardiogram showed first‐degree atrioventricular block and complete right bundle branch block (CRBBB). We planned to examine laboratory data, echocardiography, Holter monitoring, and g...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107975/ https://www.ncbi.nlm.nih.gov/pubmed/27867531 http://dx.doi.org/10.1002/ehf2.12095 |
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author | Okabe, Toshitaka Yakushiji, Tadayuki Hiroe, Michiaki Oyama, Yuji Igawa, Wataru Ono, Morio Kido, Takehiko Ebara, Seitaro Yamashita, Kennosuke Yamamoto, Myong Hwa Saito, Shigeo Hoshimoto, Koichi Kisaki, Amemiya Isomura, Naoei Araki, Hiroshi Ochiai, Masahiko |
author_facet | Okabe, Toshitaka Yakushiji, Tadayuki Hiroe, Michiaki Oyama, Yuji Igawa, Wataru Ono, Morio Kido, Takehiko Ebara, Seitaro Yamashita, Kennosuke Yamamoto, Myong Hwa Saito, Shigeo Hoshimoto, Koichi Kisaki, Amemiya Isomura, Naoei Araki, Hiroshi Ochiai, Masahiko |
author_sort | Okabe, Toshitaka |
collection | PubMed |
description | A 32‐year‐old man presented with palpitation. He was diagnosed with pulmonary sarcoidosis by lung biopsy. The electrocardiogram showed first‐degree atrioventricular block and complete right bundle branch block (CRBBB). We planned to examine laboratory data, echocardiography, Holter monitoring, and gallium‐67 scintigraphy. Before he went through all these exams, he developed ventricular tachycardia. After defibrillation was performed, his electrocardiogram revealed complete atrioventricular block. We observed elevation of serum angiotensin‐converting enzyme levels. In addition, both of gallium‐67 scintigraphy and (18)F‐fluorodeoxyglucose positron emission tomography showed abnormal uptake in the ventricular septum. We diagnosed the patient with cardiac sarcoidosis associated with these arrhythmias. We started treatment with methylprednisolone pulse therapy (1 g daily). After 3 days of steroid pulse therapy, we administered prednisolone 30 mg daily. On day 15, electrocardiogram changed from complete atrioventricular block to first‐degree atrioventricular block and CRBBB. He was discharged with no progression with cardiac sarcoidosis for 2 years. |
format | Online Article Text |
id | pubmed-5107975 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-51079752016-11-16 Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction Okabe, Toshitaka Yakushiji, Tadayuki Hiroe, Michiaki Oyama, Yuji Igawa, Wataru Ono, Morio Kido, Takehiko Ebara, Seitaro Yamashita, Kennosuke Yamamoto, Myong Hwa Saito, Shigeo Hoshimoto, Koichi Kisaki, Amemiya Isomura, Naoei Araki, Hiroshi Ochiai, Masahiko ESC Heart Fail Case Reports A 32‐year‐old man presented with palpitation. He was diagnosed with pulmonary sarcoidosis by lung biopsy. The electrocardiogram showed first‐degree atrioventricular block and complete right bundle branch block (CRBBB). We planned to examine laboratory data, echocardiography, Holter monitoring, and gallium‐67 scintigraphy. Before he went through all these exams, he developed ventricular tachycardia. After defibrillation was performed, his electrocardiogram revealed complete atrioventricular block. We observed elevation of serum angiotensin‐converting enzyme levels. In addition, both of gallium‐67 scintigraphy and (18)F‐fluorodeoxyglucose positron emission tomography showed abnormal uptake in the ventricular septum. We diagnosed the patient with cardiac sarcoidosis associated with these arrhythmias. We started treatment with methylprednisolone pulse therapy (1 g daily). After 3 days of steroid pulse therapy, we administered prednisolone 30 mg daily. On day 15, electrocardiogram changed from complete atrioventricular block to first‐degree atrioventricular block and CRBBB. He was discharged with no progression with cardiac sarcoidosis for 2 years. John Wiley and Sons Inc. 2016-07-04 /pmc/articles/PMC5107975/ /pubmed/27867531 http://dx.doi.org/10.1002/ehf2.12095 Text en © 2016 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Okabe, Toshitaka Yakushiji, Tadayuki Hiroe, Michiaki Oyama, Yuji Igawa, Wataru Ono, Morio Kido, Takehiko Ebara, Seitaro Yamashita, Kennosuke Yamamoto, Myong Hwa Saito, Shigeo Hoshimoto, Koichi Kisaki, Amemiya Isomura, Naoei Araki, Hiroshi Ochiai, Masahiko Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
title | Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
title_full | Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
title_fullStr | Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
title_full_unstemmed | Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
title_short | Steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
title_sort | steroid pulse therapy was effective for cardiac sarcoidosis with ventricular tachycardia and systolic dysfunction |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107975/ https://www.ncbi.nlm.nih.gov/pubmed/27867531 http://dx.doi.org/10.1002/ehf2.12095 |
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