Cargando…

SAV742, a Novel AraC-Family Regulator from Streptomyces avermitilis, Controls Avermectin Biosynthesis, Cell Growth and Development

Avermectins are useful anthelmintic antibiotics produced by Streptomyces avermitilis. We demonstrated that a novel AraC-family transcriptional regulator in this species, SAV742, is a global regulator that negatively controls avermectin biosynthesis and cell growth, but positively controls morphologi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Di, Zhu, Jianya, Chen, Zhi, Li, Jilun, Wen, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107987/ https://www.ncbi.nlm.nih.gov/pubmed/27841302 http://dx.doi.org/10.1038/srep36915

Ejemplares similares

SAV4189, a MarR-Family Regulator in Streptomyces avermitilis, Activates Avermectin Biosynthesis
por: Guo, Jia, et al.
Publicado: (2018)

A Novel TetR Family Transcriptional Regulator, SAV576, Negatively Controls Avermectin Biosynthesis in Streptomyces avermitilis
por: Guo, Jia, et al.
Publicado: (2013)

Two Adjacent and Similar TetR Family Transcriptional Regulator Genes, SAV577 and SAV576, Co-Regulate Avermectin Production in Streptomyces avermitilis
por: Guo, Jia, et al.
Publicado: (2014)

AvaR1, a Butenolide-Type Autoregulator Receptor in Streptomyces avermitilis, Directly Represses Avenolide and Avermectin Biosynthesis and Multiple Physiological Responses
por: Zhu, Jianya, et al.
Publicado: (2017)

An Alternative σ Factor, σ(8), Controls Avermectin Production and Multiple Stress Responses in Streptomyces avermitilis
por: Sun, Di, et al.
Publicado: (2017)

Interrogation of Streptomyces avermitilis for efficient production of avermectins
por: Chen, Jinsong, et al.
Publicado: (2016)

Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis
por: Kim, Myoun-Su, et al.
Publicado: (2017)

Redox-sensing regulator Rex regulates aerobic metabolism, morphological differentiation, and avermectin production in Streptomyces avermitilis
por: Liu, Xingchao, et al.
Publicado: (2017)

Organic Peroxide-Sensing Repressor OhrR Regulates Organic Hydroperoxide Stress Resistance and Avermectin Production in Streptomyces avermitilis
por: Sun, Meng, et al.
Publicado: (2018)

Isolation, Characterization and Selection of Avermectin-Producing Streptomyces avermitilis Strains From Soil Samples
por: Siddique, Samia, et al.
Publicado: (2014)

Raising the avermectins production in Streptomyces avermitilis by utilizing nanosecond pulsed electric fields (nsPEFs)
por: Guo, Jinsong, et al.
Publicado: (2016)

DNA tape measurements of AraC
por: Rodgers, Michael E., et al.
Publicado: (2008)

Production and Screening of High Yield Avermectin B1b Mutant of Streptomyces avermitilis 41445 Through Mutagenesis
por: Siddique, Samia, et al.
Publicado: (2014)

Significance of Heavy-Ion Beam Irradiation-Induced Avermectin B1a Production by Engineered Streptomyces avermitilis
por: Wang, Shu-Yang, et al.
Publicado: (2017)

Chromosomal instability in Streptomyces avermitilis: major deletion in the central region and stable circularized chromosome
por: Chen, Wei, et al.
Publicado: (2010)

Kinetics of Avermectin B1b Production by Streptomyces avermitilis 41445 UV 45(m)3 in Shake Flask Culture
por: Siddique, Samia, et al.
Publicado: (2020)

AraC-Based Biosensor for the Detection of Isoprene in E. coli
por: Bhat, Shrilaxmi, et al.
Publicado: (2023)

Liposomally trapped AraCTP to overcome AraC resistance in a murine lymphoma in vitro.
por: Richardson, V. J., et al.
Publicado: (1982)

A large family of anti‐activators accompanying XylS/AraC family regulatory proteins
por: Santiago, Araceli E., et al.
Publicado: (2016)

Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator
por: Shi, Jing, et al.
Publicado: (2022)

A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT
por: Woodbrey, Anne K., et al.
Publicado: (2017)

The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria
por: Santiago, Araceli E., et al.
Publicado: (2017)

Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis
por: Evangelopoulos, Dimitrios, et al.
Publicado: (2014)

Characterization of a novel AraC/XylS-regulated family of N-acyltransferases in pathogens of the order Enterobacterales
por: Belmont-Monroy, Laura, et al.
Publicado: (2020)

Computer-Based Annotation of Putative AraC/XylS-Family Transcription Factors of Known Structure but Unknown Function
por: Schüller, Andreas, et al.
Publicado: (2012)

1.65 Å resolution structure of the AraC-family transcriptional activator ToxT from Vibrio cholerae
por: Li, Jiaqin, et al.
Publicado: (2016)

FoxR is an AraC‐like transcriptional regulator of ferrioxamine uptake in Salmonella enterica
por: Saldaña‐Ahuactzi, Zeus, et al.
Publicado: (2022)

Natural Biocombinatorics in the Polyketide Synthase Genes of the Actinobacterium Streptomyces avermitilis
por: Jenke-Kodama, Holger, et al.
Publicado: (2006)

Rationally Improving Doramectin Production in Industrial Streptomyces avermitilis Strains
por: Dang, Fujun, et al.
Publicado: (2023)

Signal amplification of araC pBAD using a standardized translation initiation region
por: Shilling, Patrick J, et al.
Publicado: (2022)

An Active Type I-E CRISPR-Cas System Identified in Streptomyces avermitilis
por: Qiu, Yi, et al.
Publicado: (2016)

Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
por: Cha, Ming C, et al.
Publicado: (2005)

Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo
por: Nishioka, Chie, et al.
Publicado: (2015)

AraC interacts with p75(NTR) transmembrane domain to induce cell death of mature neurons
por: Lopes-Rodrigues, Vanessa, et al.
Publicado: (2023)

Characterization of the biosynthetic gene cluster for cryptic phthoxazolin A in Streptomyces avermitilis
por: Suroto, Dian Anggraini, et al.
Publicado: (2018)

Comparative genomics of Streptomyces avermitilis, Streptomyces cattleya, Streptomyces maritimus and Kitasatospora aureofaciens using a Streptomyces coelicolor microarray system
por: Hsiao, Nai-hua, et al.
Publicado: (2007)

A mannose-sensing AraC-type transcriptional activator regulates cell–cell aggregation of Vibrio cholerae
por: Lee, Hye-Young, et al.
Publicado: (2022)

Characterization of a Biflaviolin Synthase CYP158A3 from Streptomyces avermitilis and Its Role in the Biosynthesis of Secondary Metabolites
por: Lim, Young-Ran, et al.
Publicado: (2017)

Characterization of a GH Family 20 Exo-β-N-acetylhexosaminidase with Antifungal Activity from Streptomyces avermitilis
por: Shirasaka, Naoki, et al.
Publicado: (2019)

The AraC-Type Transcriptional Regulator GliR (PA3027) Activates Genes of Glycerolipid Metabolism in Pseudomonas aeruginosa
por: Kotecka, Karolina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_uk4nhkrjpt41q552o1vqdq03v4