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Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves’ Disease: An Encrypted Message Sent by Animal Models
Graves’ hyperthyroidism is caused by autoantibodies directed against the thyroid-stimulating hormone receptor (TSHR) that mimic the action of TSH. The establishment of Graves’ hyperthyroidism in experimental animals has proven to be an important approach to dissect the mechanisms of self-tolerance b...
Autores principales: | Luo, Yuqian, Yoshihara, Aya, Oda, Kenzaburo, Ishido, Yuko, Suzuki, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107990/ https://www.ncbi.nlm.nih.gov/pubmed/27895620 http://dx.doi.org/10.3389/fendo.2016.00144 |
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