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RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops
Understanding the fundamental nature of a molecular process or a biological pathway is often a catalyst for the development of new technologies in biology. Indeed, studies from late 1990s to early 2000s have uncovered multiple overlapping but functionally distinct RNA silencing pathways in plants, i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108043/ https://www.ncbi.nlm.nih.gov/pubmed/28217004 http://dx.doi.org/10.2174/1389202917666160520103117 |
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author | Guo, Qigao Liu, Qing Smith, Neil A. Liang, Guolu Wang, Ming-Bo |
author_facet | Guo, Qigao Liu, Qing Smith, Neil A. Liang, Guolu Wang, Ming-Bo |
author_sort | Guo, Qigao |
collection | PubMed |
description | Understanding the fundamental nature of a molecular process or a biological pathway is often a catalyst for the development of new technologies in biology. Indeed, studies from late 1990s to early 2000s have uncovered multiple overlapping but functionally distinct RNA silencing pathways in plants, including the posttranscriptional microRNA and small interfering RNA pathways and the transcriptional RNA-directed DNA methylation pathway. These findings have in turn been exploited for developing artificial RNA silencing technologies such as hairpin RNA, artificial microRNA, intrinsic direct repeat, 3’ UTR inverted repeat, artificial trans-acting siRNA, and virus-induced gene silencing technologies. Some of these RNA silencing technologies, such as the hairpin RNA technology, have already been widely used for genetic improvement of crop plants in agriculture. For horticultural plants, RNA silencing technologies have been used to increase disease and pest resistance, alter plant architecture and flowering time, improve commercial traits of fruits and flowers, enhance nutritional values, remove toxic compounds and allergens, and develop high-value industrial products. In this article we aim to provide an overview of the RNA silencing pathways in plants, summarize the existing RNA silencing technologies, and review the current progress in applying these technologies for the improvement of agricultural crops particularly horticultural crops. |
format | Online Article Text |
id | pubmed-5108043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-51080432017-06-01 RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops Guo, Qigao Liu, Qing Smith, Neil A. Liang, Guolu Wang, Ming-Bo Curr Genomics Article Understanding the fundamental nature of a molecular process or a biological pathway is often a catalyst for the development of new technologies in biology. Indeed, studies from late 1990s to early 2000s have uncovered multiple overlapping but functionally distinct RNA silencing pathways in plants, including the posttranscriptional microRNA and small interfering RNA pathways and the transcriptional RNA-directed DNA methylation pathway. These findings have in turn been exploited for developing artificial RNA silencing technologies such as hairpin RNA, artificial microRNA, intrinsic direct repeat, 3’ UTR inverted repeat, artificial trans-acting siRNA, and virus-induced gene silencing technologies. Some of these RNA silencing technologies, such as the hairpin RNA technology, have already been widely used for genetic improvement of crop plants in agriculture. For horticultural plants, RNA silencing technologies have been used to increase disease and pest resistance, alter plant architecture and flowering time, improve commercial traits of fruits and flowers, enhance nutritional values, remove toxic compounds and allergens, and develop high-value industrial products. In this article we aim to provide an overview of the RNA silencing pathways in plants, summarize the existing RNA silencing technologies, and review the current progress in applying these technologies for the improvement of agricultural crops particularly horticultural crops. Bentham Science Publishers 2016-12 2016-12 /pmc/articles/PMC5108043/ /pubmed/28217004 http://dx.doi.org/10.2174/1389202917666160520103117 Text en ©2016 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Guo, Qigao Liu, Qing Smith, Neil A. Liang, Guolu Wang, Ming-Bo RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops |
title | RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops |
title_full | RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops |
title_fullStr | RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops |
title_full_unstemmed | RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops |
title_short | RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops |
title_sort | rna silencing in plants: mechanisms, technologies and applications in horticultural crops |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108043/ https://www.ncbi.nlm.nih.gov/pubmed/28217004 http://dx.doi.org/10.2174/1389202917666160520103117 |
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