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Exploiting the dynamic properties of covalent modification cycle for the design of synthetic analog biomolecular circuitry
BACKGROUND: Cycles of covalent modification are ubiquitous motifs in cellular signalling. Although such signalling cycles are implemented via a highly concise set of chemical reactions, they have been shown to be capable of producing multiple distinct input-output mapping behaviours – ultrasensitive...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108087/ https://www.ncbi.nlm.nih.gov/pubmed/27872658 http://dx.doi.org/10.1186/s13036-016-0036-1 |