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Newborn with meroanencephaly: Surviving all odds
Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms – meroanencephaly, holoanencephaly, and craniorachischisis. Me...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108127/ https://www.ncbi.nlm.nih.gov/pubmed/27857793 http://dx.doi.org/10.4103/1817-1745.193360 |
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author | Khan, Iraj Alam Firdaus, Uzma Ali, Syed Manazir Asghar, Imran |
author_facet | Khan, Iraj Alam Firdaus, Uzma Ali, Syed Manazir Asghar, Imran |
author_sort | Khan, Iraj Alam |
collection | PubMed |
description | Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms – meroanencephaly, holoanencephaly, and craniorachischisis. Meroanencephaly is considered to be the classic form of anencephaly. It manifests as a lack of cranial vault bones and exposed dorsal neural tissue resulting from defective neural tube closure in the very early period of gestation. Antenatally, the diagnosis may be suggested by ultrasound examination and by elevated maternal alpha-fetoprotein level. Here, we describe a case of meroanencephaly who was discharged from the hospital in fair condition despite the life-threatening anomaly. |
format | Online Article Text |
id | pubmed-5108127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-51081272016-11-17 Newborn with meroanencephaly: Surviving all odds Khan, Iraj Alam Firdaus, Uzma Ali, Syed Manazir Asghar, Imran J Pediatr Neurosci Case Report Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms – meroanencephaly, holoanencephaly, and craniorachischisis. Meroanencephaly is considered to be the classic form of anencephaly. It manifests as a lack of cranial vault bones and exposed dorsal neural tissue resulting from defective neural tube closure in the very early period of gestation. Antenatally, the diagnosis may be suggested by ultrasound examination and by elevated maternal alpha-fetoprotein level. Here, we describe a case of meroanencephaly who was discharged from the hospital in fair condition despite the life-threatening anomaly. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5108127/ /pubmed/27857793 http://dx.doi.org/10.4103/1817-1745.193360 Text en Copyright: © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Khan, Iraj Alam Firdaus, Uzma Ali, Syed Manazir Asghar, Imran Newborn with meroanencephaly: Surviving all odds |
title | Newborn with meroanencephaly: Surviving all odds |
title_full | Newborn with meroanencephaly: Surviving all odds |
title_fullStr | Newborn with meroanencephaly: Surviving all odds |
title_full_unstemmed | Newborn with meroanencephaly: Surviving all odds |
title_short | Newborn with meroanencephaly: Surviving all odds |
title_sort | newborn with meroanencephaly: surviving all odds |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108127/ https://www.ncbi.nlm.nih.gov/pubmed/27857793 http://dx.doi.org/10.4103/1817-1745.193360 |
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