Cargando…

Newborn with meroanencephaly: Surviving all odds

Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms – meroanencephaly, holoanencephaly, and craniorachischisis. Me...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Iraj Alam, Firdaus, Uzma, Ali, Syed Manazir, Asghar, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108127/
https://www.ncbi.nlm.nih.gov/pubmed/27857793
http://dx.doi.org/10.4103/1817-1745.193360
_version_ 1782467312754884608
author Khan, Iraj Alam
Firdaus, Uzma
Ali, Syed Manazir
Asghar, Imran
author_facet Khan, Iraj Alam
Firdaus, Uzma
Ali, Syed Manazir
Asghar, Imran
author_sort Khan, Iraj Alam
collection PubMed
description Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms – meroanencephaly, holoanencephaly, and craniorachischisis. Meroanencephaly is considered to be the classic form of anencephaly. It manifests as a lack of cranial vault bones and exposed dorsal neural tissue resulting from defective neural tube closure in the very early period of gestation. Antenatally, the diagnosis may be suggested by ultrasound examination and by elevated maternal alpha-fetoprotein level. Here, we describe a case of meroanencephaly who was discharged from the hospital in fair condition despite the life-threatening anomaly.
format Online
Article
Text
id pubmed-5108127
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-51081272016-11-17 Newborn with meroanencephaly: Surviving all odds Khan, Iraj Alam Firdaus, Uzma Ali, Syed Manazir Asghar, Imran J Pediatr Neurosci Case Report Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms – meroanencephaly, holoanencephaly, and craniorachischisis. Meroanencephaly is considered to be the classic form of anencephaly. It manifests as a lack of cranial vault bones and exposed dorsal neural tissue resulting from defective neural tube closure in the very early period of gestation. Antenatally, the diagnosis may be suggested by ultrasound examination and by elevated maternal alpha-fetoprotein level. Here, we describe a case of meroanencephaly who was discharged from the hospital in fair condition despite the life-threatening anomaly. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5108127/ /pubmed/27857793 http://dx.doi.org/10.4103/1817-1745.193360 Text en Copyright: © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Khan, Iraj Alam
Firdaus, Uzma
Ali, Syed Manazir
Asghar, Imran
Newborn with meroanencephaly: Surviving all odds
title Newborn with meroanencephaly: Surviving all odds
title_full Newborn with meroanencephaly: Surviving all odds
title_fullStr Newborn with meroanencephaly: Surviving all odds
title_full_unstemmed Newborn with meroanencephaly: Surviving all odds
title_short Newborn with meroanencephaly: Surviving all odds
title_sort newborn with meroanencephaly: surviving all odds
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108127/
https://www.ncbi.nlm.nih.gov/pubmed/27857793
http://dx.doi.org/10.4103/1817-1745.193360
work_keys_str_mv AT khanirajalam newbornwithmeroanencephalysurvivingallodds
AT firdausuzma newbornwithmeroanencephalysurvivingallodds
AT alisyedmanazir newbornwithmeroanencephalysurvivingallodds
AT asgharimran newbornwithmeroanencephalysurvivingallodds