Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells

Metabolic reprogramming is critical to oncogenesis, but the emergence and function of this profound reorganization remain poorly understood. Here we find that cooperating oncogenic mutations drive large-scale metabolic reprogramming, which is both intrinsic to cancer cells and obligatory for the tra...

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Detalles Bibliográficos
Autores principales: Smith, Bradley, Schafer, Xenia L., Ambeskovic, Aslihan, Spencer, Cody M., Land, Hartmut, Munger, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108179/
https://www.ncbi.nlm.nih.gov/pubmed/27732857
http://dx.doi.org/10.1016/j.celrep.2016.09.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108179/
https://www.ncbi.nlm.nih.gov/pubmed/27732857
http://dx.doi.org/10.1016/j.celrep.2016.09.045

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