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Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide, and systemic chemotherapy is the major treatment strategy for late-stage HCC patients. Poor prognosis following chemotherapy is the general outcome owing to recurrent resistance. Recent studies have suggeste...

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Detalles Bibliográficos
Autores principales: Chi, Hsiang-Cheng, Chen, Shen-Liang, Cheng, Yi-Hung, Lin, Tzu-Kang, Tsai, Chung-Ying, Tsai, Ming-Ming, Lin, Yang-Hsiang, Huang, Ya-Hui, Lin, Kwang-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108316/
https://www.ncbi.nlm.nih.gov/pubmed/27490929
http://dx.doi.org/10.1038/cddis.2016.227