Cargando…

Bcl-x(L) is an oncogenic driver in colorectal cancer

Colorectal cancer (CRC) is the second most common malignant neoplasia in women and men worldwide. The B-cell lymphoma 2 (Bcl-2) protein family is mainly known for its pivotal role in the regulation of the mitochondrial death pathway. Anti-apoptotic Bcl-2 proteins may provide survival benefits and in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scherr, Anna-Lena, Gdynia, Georg, Salou, Mariam, Radhakrishnan, Praveen, Duglova, Katarina, Heller, Anette, Keim, Sophia, Kautz, Nicole, Jassowicz, Adam, Elssner, Christin, He, You-Wen, Jaeger, Dirk, Heikenwalder, Mathias, Schneider, Martin, Weber, Achim, Roth, Wilfried, Schulze-Bergkamen, Henning, Koehler, Bruno Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108319/ https://www.ncbi.nlm.nih.gov/pubmed/27537525 http://dx.doi.org/10.1038/cddis.2016.233

Ejemplares similares

Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling
por: Koehler, Bruno Christian, et al.
Publicado: (2015)

Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells
por: Koehler, Bruno Christian, et al.
Publicado: (2014)

Beyond Cell Death – Antiapoptotic Bcl-2 Proteins Regulate Migration and Invasion of Colorectal Cancer Cells In Vitro
por: Koehler, Bruno Christian, et al.
Publicado: (2013)

Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells
por: Scherr, Anna-Lena, et al.
Publicado: (2020)

Nuclear Expression of the Deubiquitinase CYLD Is Associated with Improved Survival in Human Hepatocellular Carcinoma
por: Welte, Stefan, et al.
Publicado: (2014)

Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer
por: Scherr, Anna-Lena, et al.
Publicado: (2020)

Distinct Activities of Glycolytic Enzymes Identify Chronic Lymphocytic Leukemia Patients with a more Aggressive Course and Resistance to Chemo-Immunotherapy
por: Gdynia, Georg, et al.
Publicado: (2018)

Hit-and-run lymphomagenesis by the Bcl6 oncogene
por: Green, Michael R, et al.
Publicado: (2014)

Wnt status-dependent oncogenic role of BCL9 and BCL9L in hepatocellular carcinoma
por: Huge, Nicole, et al.
Publicado: (2019)

Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma
por: Dupont, Thibault, et al.
Publicado: (2015)

HMGB1: The metabolic weapon in the arsenal of NK cells
por: Cerwenka, Adelheid, et al.
Publicado: (2016)

BCL2 oncogene translocation is mediated by a chi-like consensus
Publicado: (1992)

Targeting Bcl-2 stability to sensitize cells harboring oncogenic ras
por: Peng, Bo, et al.
Publicado: (2015)

BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis
por: Louwen, Frank, et al.
Publicado: (2022)

Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
por: Schulze-Bergkamen, Henning, et al.
Publicado: (2006)

BCL3 exerts an oncogenic function by regulating STAT3 in human cervical cancer
por: Zhao, Hu, et al.
Publicado: (2016)

BCL11A Is Oncogenic and Predicts Poor Outcomes in Natural Killer/T-Cell Lymphoma
por: Shi, Hongyun, et al.
Publicado: (2020)

DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
por: Lai, Anne Y., et al.
Publicado: (2010)

The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis
por: Zatula, Nathalie, et al.
Publicado: (2014)

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent
por: You, Ming-Liang, et al.
Publicado: (2017)

N52 monodeamidated Bcl–x(L) shows impaired oncogenic properties in vivo and in vitro
por: Beaumatin, Florian, et al.
Publicado: (2016)

Targeting Oncogenic Mutant p53 and BCL-2 for Small Cell Lung Cancer Treatment
por: Neely, Victoria, et al.
Publicado: (2023)

Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins
por: Pöhlmann, Christopher, et al.
Publicado: (2020)

BCL2 genotypes and prostate cancer survival
por: Renner, Wilfried, et al.
Publicado: (2017)

Oncogenic Collaboration of the Cyclin D1 (PRAD1, bcl‐1) Gene with a Mutated p53 and an Activated ras Oncogene in Neoplastic Transformation
por: Uchimaru, Kaoru, et al.
Publicado: (1996)

The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration
por: Gdynia, Georg, et al.
Publicado: (2016)

Acetylation of the Proto-Oncogene EVI1 Abrogates Bcl-xL Promoter Binding and Induces Apoptosis
por: Pradhan, Anjan Kumar, et al.
Publicado: (2011)

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy
por: Fabre, Marie-Sophie, et al.
Publicado: (2020)

Development of Dual Functional Nucleic Acid Delivery Nanosystem for DNA Induced Silencing of Bcl-2 Oncogene
por: Karimi, Somayeh, et al.
Publicado: (2020)

SAT-LB056 Is AIP a Tumor Suppressor or an Oncogene? AIP as a Novel Regulator of the Oncogene BCL6 in Diffuse Large B Cell Lymphoma
por: BARRY, SAYKA, et al.
Publicado: (2019)

Probability matching does not decrease under cognitive load: A preregistered failure to replicate
por: Schulze, Christin, et al.
Publicado: (2019)

A Pan-Cancer Analysis of the Oncogenic Role of BCL7B: A Potential Biomarker for Prognosis and Immunotherapy
por: Yang, Dinglong, et al.
Publicado: (2022)

MEF2B mutations lead to deregulated expression of the BCL6 oncogene in Diffuse Large B cell Lymphoma
por: Ying, Carol Y., et al.
Publicado: (2013)

Wnt/β-Catenin Signalling and Its Cofactor BCL9L Have an Oncogenic Effect in Bladder Cancer Cells
por: Kotolloshi, Roland, et al.
Publicado: (2022)

Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity
por: Huyghe, A., et al.
Publicado: (2022)

B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric Cancers
por: McLachlan, Tabitha, et al.
Publicado: (2022)

Distinct B-Cell Specific Transcriptional Contexts of the BCL2 Oncogene Impact Pre-Malignant Development in Mouse Models
por: Zawil, Lina, et al.
Publicado: (2022)

The relationship between multiple traumatic events and the severity of posttraumatic stress disorder symptoms – evidence for a cognitive link
por: Kube, Tobias, et al.
Publicado: (2023)

Induction treatment in high-grade B-cell lymphoma with a concurrent MYC and BCL2 and/or BCL6 rearrangement: a systematic review and meta-analysis
por: Zeremski, Vanja, et al.
Publicado: (2023)

Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy
por: Rahbari, Nuh N, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_e00o5bgkudvpf7k7bltrget76p