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Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a potent cancer cell-specific apoptosis-inducing cytokine with little toxicity to most normal cells. However, acquired resistance of cancer cells to TRAIL is a roadblock. Agents that can either potentiate the effect of TRAIL or...

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Detalles Bibliográficos
Autores principales:	Chen, Lei, Meng, Yue, Sun, Qi, Zhang, Zhongyu, Guo, Xiaoqing, Sheng, Xiaotong, Tai, Guihua, Cheng, Hairong, Zhou, Yifa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108320/ https://www.ncbi.nlm.nih.gov/pubmed/27512955 http://dx.doi.org/10.1038/cddis.2016.234

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