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Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics

Recurrence of gastrointestinal adenocarcinomas after surgery and chemotherapy may be attributed, in part, to the presence of a small population of tumor-initiating cancer stem cells (CSC). The expression of galectin-3 (Gal3), a multifunctional oncolectin, has been associated with biological behavior...

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Detalles Bibliográficos
Autores principales: Ilmer, Matthias, Mazurek, Nachman, Byrd, James C, Ramirez, Karen, Hafley, Margarete, Alt, Eckhard, Vykoukal, Jody, Bresalier, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108324/
https://www.ncbi.nlm.nih.gov/pubmed/27512958
http://dx.doi.org/10.1038/cddis.2016.239