Cargando…
Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics
Recurrence of gastrointestinal adenocarcinomas after surgery and chemotherapy may be attributed, in part, to the presence of a small population of tumor-initiating cancer stem cells (CSC). The expression of galectin-3 (Gal3), a multifunctional oncolectin, has been associated with biological behavior...
Autores principales: | Ilmer, Matthias, Mazurek, Nachman, Byrd, James C, Ramirez, Karen, Hafley, Margarete, Alt, Eckhard, Vykoukal, Jody, Bresalier, Robert S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108324/ https://www.ncbi.nlm.nih.gov/pubmed/27512958 http://dx.doi.org/10.1038/cddis.2016.239 |
Ejemplares similares
-
Low expression of galectin-3 is associated with poor survival in node-positive breast cancers and mesenchymal phenotype in breast cancer stem cells
por: Ilmer, Matthias, et al.
Publicado: (2016) -
Overexpressed Galectin-3 in Pancreatic Cancer Induces Cell Proliferation and Invasion by Binding Ras and Activating Ras Signaling
por: Song, Shumei, et al.
Publicado: (2012) -
Improved Method for Isolation of Neonatal Rat Cardiomyocytes with Increased Yield of C-Kit+ Cardiac Progenitor Cells
por: Rutering, Jennifer, et al.
Publicado: (2015) -
JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAIL-induced apoptosis without affecting the physiology of normal tissue resident stem cells
por: Recio-Boiles, Alejandro, et al.
Publicado: (2016) -
Identification of galectin-1 as a novel mediator for chemoresistance in chronic myeloid leukemia cells
por: Luo, Wu, et al.
Publicado: (2016)