Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

To identify risk variants for multiple myeloma (MM), we conducted a genome-wide association study totaling of 1,675 MM cases and 5,903 controls. We identified risk loci for MM at 3p22.1 (rs1052501, ULK4; odds ratio [OR]=1.32; P=7.47x10(-9)) and 7p15.3 (rs4487645, OR=1.38; P=3.33x10(-15)). In additio...

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Detalles Bibliográficos
Autores principales: Broderick, Peter, Chubb, Daniel, Johnson, David C, Weinhold, Niels, Försti, Asta, Lloyd, Amy, Olver, Bianca, Ma, Yussanne, Dobbins, Sara E, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Childs, J. Anthony, Ross, Fiona M, Jackson, Graham H, Neben, Kai, Jauch, Anna, Hoffmann, Per, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Tomlinson, Ian P, Goldschmidt, Hartmut, Hemminki, Kari, Morgan, Gareth J, Houlston, Richard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108406/
https://www.ncbi.nlm.nih.gov/pubmed/22120009
http://dx.doi.org/10.1038/ng.993

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