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Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments

Insufficient advances in the development of effective therapeutic treatments of sporadic Alzheimer's Disease (sAD) to date are largely due to the lack of sAD-relevant animal models. While the vast majority of models do recapitulate AD's hallmarks of plaques and tangles by virtue of tau and...

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Detalles Bibliográficos
Autores principales: Coronas-Samano, Guillermo, Baker, Keeley L., Tan, Winston J. T., Ivanova, Alla V., Verhagen, Justus V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108791/
https://www.ncbi.nlm.nih.gov/pubmed/27895577
http://dx.doi.org/10.3389/fnagi.2016.00268