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Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models
Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD), is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addressed. On the other hand, disorder of gut microbiota...
Autores principales: | Su, Danmei, Nie, Yuanyang, Zhu, Airu, Chen, Zishuo, Wu, Pengfei, Zhang, Li, Luo, Mei, Sun, Qun, Cai, Linbi, Lai, Yuchen, Xiao, Zhixiong, Duan, Zhongping, Zheng, Sujun, Wu, Guihui, Hu, Richard, Tsukamoto, Hidekazu, Lugea, Aurelia, Liu, Zhenqui, Pandol, Stephen J., Han, Yuan-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108805/ https://www.ncbi.nlm.nih.gov/pubmed/27895587 http://dx.doi.org/10.3389/fphys.2016.00498 |
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