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Cyclooxygenase-2: A Role in Cancer Stem Cell Survival and Repopulation of Cancer Cells during Therapy
Cyclooxygenase-2 (COX-2) is an inducible form of the enzyme that catalyses the synthesis of prostanoids, including prostaglandin E2 (PGE(2)), a major mediator of inflammation and angiogenesis. COX-2 is overexpressed in cancer cells and is associated with progressive tumour growth, as well as resista...
| Autores principales: | , , |
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| 格式: | Online 文件 Texto |
| 语言: | English |
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Hindawi Publishing Corporation
2016
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| 主题: | |
| 在线阅读: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108861/ https://www.ncbi.nlm.nih.gov/pubmed/27882058 http://dx.doi.org/10.1155/2016/2048731 |