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Profiling ribonucleotide and deoxyribonucleotide pools perturbed by gemcitabine in human non-small cell lung cancer cells

In this study, we investigated the dosage effect of gemcitabine, an inhibitor of ribonucleotide reductase (RR), on cellular levels of ribonucleotides and deoxyribonucleotides using high performance liquid chromatography-electrospray ionization tandem mass spectrometric method. As anticipated, after...

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Detalles Bibliográficos
Autores principales:	Guo, Jian-Ru, Chen, Qian-Qian, Lam, Christopher Wai Kei, Wang, Cai-Yun, Wong, Vincent Kam Wai, Chang, Zee-Fen, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109029/ https://www.ncbi.nlm.nih.gov/pubmed/27845436 http://dx.doi.org/10.1038/srep37250

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