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A pH‐ and ionic strength‐dependent conformational change in the neck region regulates DNGR‐1 function in dendritic cells

DNGR‐1 is receptor expressed by certain dendritic cell (DC) subsets and by DC precursors in mouse. It possesses a C‐type lectin‐like domain (CTLD) followed by a poorly characterized neck region coupled to a transmembrane region and short intracellular tail. The CTLD of DNGR‐1 binds F‐actin exposed b...

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Detalles Bibliográficos
Autores principales:	Hanč, Pavel, Schulz, Oliver, Fischbach, Hanna, Martin, Stephen R, Kjær, Svend, Reis e Sousa, Caetano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109244/ https://www.ncbi.nlm.nih.gov/pubmed/27753620 http://dx.doi.org/10.15252/embj.201694695

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