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Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress

Thioredoxin reductase 1 (TrxR1) is a pivotal intracellular redox sensor and antioxidant enzyme. On the other hand, overexpression of TrxR1 is closely correlated with the initiation of various tumors including breast cancer, though the detailed mechanism remains unclear. Here we investigated the role...

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Detalles Bibliográficos
Autores principales:	Dong, Chaoran, Zhang, Lei, Sun, Ruoxuan, Liu, Jianying, Yin, Hanwei, Li, Xiaoxiao, Zheng, Xiaoqing, Zeng, Huihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109291/ https://www.ncbi.nlm.nih.gov/pubmed/27845427 http://dx.doi.org/10.1038/srep36860

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