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Systemic Radical Scavenger Treatment of a Mouse Model of Rett Syndrome: Merits and Limitations of the Vitamin E Derivative Trolox
Rett syndrome (RTT) is a severe neurodevelopmental disorder typically arising from spontaneous mutations in the X-chromosomal methyl-CpG binding protein 2 (MECP2) gene. The almost exclusively female Rett patients show an apparently normal development during their first 6–18 months of life. Subsequen...
Autores principales: | Janc, Oliwia A., Hüser, Marc A., Dietrich, Katharina, Kempkes, Belinda, Menzfeld, Christiane, Hülsmann, Swen, Müller, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109403/ https://www.ncbi.nlm.nih.gov/pubmed/27895554 http://dx.doi.org/10.3389/fncel.2016.00266 |
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