A multi-marker association method for genome-wide association studies without the need for population structure correction

All common genome-wide association (GWA) methods rely on population structure correction, to avoid false genotype-to-phenotype associations. However, population structure correction is a stringent penalization, which also impedes identification of real associations. Using recent statistical advances...

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Detalles Bibliográficos
Autores principales: Klasen, Jonas R., Barbez, Elke, Meier, Lukas, Meinshausen, Nicolai, Bühlmann, Peter, Koornneef, Maarten, Busch, Wolfgang, Schneeberger, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109549/
https://www.ncbi.nlm.nih.gov/pubmed/27830750
http://dx.doi.org/10.1038/ncomms13299

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