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Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes

Objective/Background: We examined the rates, predictors, and outcomes [mortality risk (MR), length of stay (LOS), and total charges (TC)] of sleep disturbances in older hospitalized patients. Patients/Methods: Using the U.S. Nationwide Inpatient Sample database (2002–2012), older patients (≥60 years...

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Autores principales: Gamaldo, Alyssa A., Beydoun, May A., Beydoun, Hind A., Liang, Hailun, Salas, Rachel E., Zonderman, Alan B., Gamaldo, Charlene E., Eid, Shaker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109617/
https://www.ncbi.nlm.nih.gov/pubmed/27895576
http://dx.doi.org/10.3389/fnagi.2016.00266
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author Gamaldo, Alyssa A.
Beydoun, May A.
Beydoun, Hind A.
Liang, Hailun
Salas, Rachel E.
Zonderman, Alan B.
Gamaldo, Charlene E.
Eid, Shaker M.
author_facet Gamaldo, Alyssa A.
Beydoun, May A.
Beydoun, Hind A.
Liang, Hailun
Salas, Rachel E.
Zonderman, Alan B.
Gamaldo, Charlene E.
Eid, Shaker M.
author_sort Gamaldo, Alyssa A.
collection PubMed
description Objective/Background: We examined the rates, predictors, and outcomes [mortality risk (MR), length of stay (LOS), and total charges (TC)] of sleep disturbances in older hospitalized patients. Patients/Methods: Using the U.S. Nationwide Inpatient Sample database (2002–2012), older patients (≥60 years) were selected and rates of insomnia, obstructive sleep apnea (OSA) and other sleep disturbances (OSD) were estimated using ICD-9CM. TC, adjusted for inflation, was of primary interest, while MR and LOS were secondary outcomes. Multivariable regression analyses were conducted. Results: Of 35,258,031 older adults, 263,865 (0.75%) had insomnia, 750,851 (2.13%) OSA and 21,814 (0.06%) OSD. Insomnia rates increased significantly (0.27% in 2002 to 1.29 in 2012, P-trend < 0.001), with a similar trend observed for OSA (1.47 in 2006 to 5.01 in 2012, P-trend < 0.001). TC (2012 $) for insomnia-related hospital admission increased over time from $22,250 in 2002 to $31,527 in 2012, and increased similarly for OSA and OSD; while LOS and MR both decreased. Women with any sleep disturbance had lower MR and TC than men, while Whites had consistently higher odds of insomnia, OSA, and OSD than older Blacks and Hispanics. Co-morbidities such as depression, cardiovascular risk factors, and neurological disorders steadily increased over time in patients with sleep disturbances. Conclusion: TC increased over time in patients with sleep disturbances while LOS and MR decreased. Further, research should focus on identifying the mechanisms that explain the association between increasing sleep disturbance rates and expenditures within hospital settings and the potential hospital expenditures of unrecognized sleep disturbances in the elderly.
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spelling pubmed-51096172016-11-28 Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes Gamaldo, Alyssa A. Beydoun, May A. Beydoun, Hind A. Liang, Hailun Salas, Rachel E. Zonderman, Alan B. Gamaldo, Charlene E. Eid, Shaker M. Front Aging Neurosci Neuroscience Objective/Background: We examined the rates, predictors, and outcomes [mortality risk (MR), length of stay (LOS), and total charges (TC)] of sleep disturbances in older hospitalized patients. Patients/Methods: Using the U.S. Nationwide Inpatient Sample database (2002–2012), older patients (≥60 years) were selected and rates of insomnia, obstructive sleep apnea (OSA) and other sleep disturbances (OSD) were estimated using ICD-9CM. TC, adjusted for inflation, was of primary interest, while MR and LOS were secondary outcomes. Multivariable regression analyses were conducted. Results: Of 35,258,031 older adults, 263,865 (0.75%) had insomnia, 750,851 (2.13%) OSA and 21,814 (0.06%) OSD. Insomnia rates increased significantly (0.27% in 2002 to 1.29 in 2012, P-trend < 0.001), with a similar trend observed for OSA (1.47 in 2006 to 5.01 in 2012, P-trend < 0.001). TC (2012 $) for insomnia-related hospital admission increased over time from $22,250 in 2002 to $31,527 in 2012, and increased similarly for OSA and OSD; while LOS and MR both decreased. Women with any sleep disturbance had lower MR and TC than men, while Whites had consistently higher odds of insomnia, OSA, and OSD than older Blacks and Hispanics. Co-morbidities such as depression, cardiovascular risk factors, and neurological disorders steadily increased over time in patients with sleep disturbances. Conclusion: TC increased over time in patients with sleep disturbances while LOS and MR decreased. Further, research should focus on identifying the mechanisms that explain the association between increasing sleep disturbance rates and expenditures within hospital settings and the potential hospital expenditures of unrecognized sleep disturbances in the elderly. Frontiers Media S.A. 2016-11-15 /pmc/articles/PMC5109617/ /pubmed/27895576 http://dx.doi.org/10.3389/fnagi.2016.00266 Text en Copyright © 2016 Gamaldo, Beydoun, Beydoun, Liang, Salas, Zonderman, Gamaldo and Eid. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Gamaldo, Alyssa A.
Beydoun, May A.
Beydoun, Hind A.
Liang, Hailun
Salas, Rachel E.
Zonderman, Alan B.
Gamaldo, Charlene E.
Eid, Shaker M.
Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes
title Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes
title_full Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes
title_fullStr Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes
title_full_unstemmed Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes
title_short Sleep Disturbances among Older Adults in the United States, 2002–2012: Nationwide Inpatient Rates, Predictors, and Outcomes
title_sort sleep disturbances among older adults in the united states, 2002–2012: nationwide inpatient rates, predictors, and outcomes
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109617/
https://www.ncbi.nlm.nih.gov/pubmed/27895576
http://dx.doi.org/10.3389/fnagi.2016.00266
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