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Rubidium and potassium levels are altered in Alzheimer’s disease brain and blood but not in cerebrospinal fluid
Loss of intracellular compartmentalization of potassium is a biochemical feature of Alzheimer’s disease indicating a loss of membrane integrity and mitochondrial dysfunction. We examined potassium and rubidium (a biological proxy for potassium) in brain tissue, blood fractions and cerebrospinal flui...
Autores principales: | Roberts, Blaine R., Doecke, James D., Rembach, Alan, Yévenes, L. Fernanda, Fowler, Christopher J., McLean, Catriona A., Lind, Monica, Volitakis, Irene, Masters, Colin L., Bush, Ashley I., Hare, Dominic J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109650/ https://www.ncbi.nlm.nih.gov/pubmed/27842602 http://dx.doi.org/10.1186/s40478-016-0390-8 |
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