Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX-

Concomitant deposition of amyloid -beta protein (Aβ) and neuronal tau as neurofibrillary tangles in the human brain is a hallmark of Alzheimer disease (AD). Because these deposits increase during normal aging, it has been proposed that aging brains may also undergo AD-like changes. To investigate th...

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Detalles Bibliográficos
Autores principales: Uchihara, Toshiki, Endo, Kentaro, Kondo, Hiromi, Okabayashi, Sachi, Shimozawa, Nobuhiro, Yasutomi, Yasuhiro, Adachi, Eijiro, Kimura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109723/
https://www.ncbi.nlm.nih.gov/pubmed/27842611
http://dx.doi.org/10.1186/s40478-016-0385-5

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