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Immunogenicity of porcine circovirus type 2 nucleic acid vaccine containing CpG motif for mice

BACKGROUND: This study aimed at reseaching the immune effect of porcine circovirus type 2 (PCV2) DNA vaccine containing CpG motif on mice. METHODS: A total of 40 6-week-old female BALB/c mice were randomly divided into four groups which were immunized by 18CpG-pVAX1-ORF2, pVAX1-ORF2, pVAX1 and PBS,...

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Detalles Bibliográficos
Autores principales: Li, Jun, Yu, Jiang, Xu, Shaojian, Shi, Jianli, Xu, Shengnan, Wu, Xiaoyan, Fu, Fang, Peng, Zhe, Zhang, Lingling, Zheng, Shuxuan, Yuan, Xiaoyuan, Cong, Xiaoyan, Sun, Wenbo, Cheng, Kaihui, Du, Yijun, Wu, Jiaqiang, Wang, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109731/
https://www.ncbi.nlm.nih.gov/pubmed/27842600
http://dx.doi.org/10.1186/s12985-016-0597-0