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Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases
BACKGROUND: Tumors avoid destruction by cytotoxic T cells (CTL) and natural killer (NK) cells by downregulation of classical human leukocyte antigens (HLA) and overexpression of non-classical HLA. This is the first study to investigate HLA expression in relation to histology (squamous cell carcinoma...
Autores principales: | Ferns, Debbie M., Heeren, A. Marijne, Samuels, Sanne, Bleeker, Maaike C. G., de Gruijl, Tanja D., Kenter, Gemma G., Jordanova, Ekaterina S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109766/ https://www.ncbi.nlm.nih.gov/pubmed/27895918 http://dx.doi.org/10.1186/s40425-016-0184-3 |
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