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Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection
Patients with extremely severe oligozoospermia (ESO) and cryptozoospermia (CO) are suitable using intracytoplasmic sperm injection (ICSI) as an infertility treatment. However, some andrologists are confused to distinguish ESO and CO in clinic diagnose. This study was designed for the first time to e...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109886/ https://www.ncbi.nlm.nih.gov/pubmed/26486062 http://dx.doi.org/10.4103/1008-682X.165948 |
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author | Zhu, Yong-Tong Luo, Chen Li, Yun Li, Hong Quan, Song Deng, Yong-Jian Yang, Yu Hu, Yong-Hua Tan, Wan-Long Chu, Qing-Jun |
author_facet | Zhu, Yong-Tong Luo, Chen Li, Yun Li, Hong Quan, Song Deng, Yong-Jian Yang, Yu Hu, Yong-Hua Tan, Wan-Long Chu, Qing-Jun |
author_sort | Zhu, Yong-Tong |
collection | PubMed |
description | Patients with extremely severe oligozoospermia (ESO) and cryptozoospermia (CO) are suitable using intracytoplasmic sperm injection (ICSI) as an infertility treatment. However, some andrologists are confused to distinguish ESO and CO in clinic diagnose. This study was designed for the first time to evaluate and compare patients with ESO and CO to determine whether these are useful clinical distinctions. A total of 270 infertile men in our center were classified into four groups as Group nonobstruction azoospermia (NOA, n = 44), Group ESO (n = 78), Group CO (n = 40), and Group obstruction azoospermia (OA, n = 108). Comparisons of the volume of bilateral testes, the level of follicle stimulating hormone (FSH) and inhibin B were obtained in four groups. Then comparisons of fertilization rates, cleavage rate, and excellent embryos rate were obtained when couples performed ICSI. All indexes (volume of bilateral testis, level of FSH and inhibin B) in Groups ESO and CO were no difference, while Groups OA versus NOA, OA versus ESO, and OA versus CO were significant differences (P < 0.05). The rates of fertilization were no differences in Groups ESO and CO while Groups OA versus ESO, OA versus CO were significant differences (P < 0.05). Therefore, the spermatogenic functions in patients with CO and ESO were similar, better than NOA but worse than OA. However, it would be helpful to evaluate their spermatogenesis using testicular biopsies, especially accompanied azoospermia in clinical practice. |
format | Online Article Text |
id | pubmed-5109886 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-51098862016-11-25 Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection Zhu, Yong-Tong Luo, Chen Li, Yun Li, Hong Quan, Song Deng, Yong-Jian Yang, Yu Hu, Yong-Hua Tan, Wan-Long Chu, Qing-Jun Asian J Androl Original Article Patients with extremely severe oligozoospermia (ESO) and cryptozoospermia (CO) are suitable using intracytoplasmic sperm injection (ICSI) as an infertility treatment. However, some andrologists are confused to distinguish ESO and CO in clinic diagnose. This study was designed for the first time to evaluate and compare patients with ESO and CO to determine whether these are useful clinical distinctions. A total of 270 infertile men in our center were classified into four groups as Group nonobstruction azoospermia (NOA, n = 44), Group ESO (n = 78), Group CO (n = 40), and Group obstruction azoospermia (OA, n = 108). Comparisons of the volume of bilateral testes, the level of follicle stimulating hormone (FSH) and inhibin B were obtained in four groups. Then comparisons of fertilization rates, cleavage rate, and excellent embryos rate were obtained when couples performed ICSI. All indexes (volume of bilateral testis, level of FSH and inhibin B) in Groups ESO and CO were no difference, while Groups OA versus NOA, OA versus ESO, and OA versus CO were significant differences (P < 0.05). The rates of fertilization were no differences in Groups ESO and CO while Groups OA versus ESO, OA versus CO were significant differences (P < 0.05). Therefore, the spermatogenic functions in patients with CO and ESO were similar, better than NOA but worse than OA. However, it would be helpful to evaluate their spermatogenesis using testicular biopsies, especially accompanied azoospermia in clinical practice. Medknow Publications & Media Pvt Ltd 2016 2015-10-20 /pmc/articles/PMC5109886/ /pubmed/26486062 http://dx.doi.org/10.4103/1008-682X.165948 Text en Copyright: © 2016 AJA, SIMM & SJTU http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Zhu, Yong-Tong Luo, Chen Li, Yun Li, Hong Quan, Song Deng, Yong-Jian Yang, Yu Hu, Yong-Hua Tan, Wan-Long Chu, Qing-Jun Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
title | Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
title_full | Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
title_fullStr | Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
title_full_unstemmed | Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
title_short | Differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
title_sort | differences and similarities between extremely severe oligozoospermia and cryptozoospermia in intracytoplasmic sperm injection |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109886/ https://www.ncbi.nlm.nih.gov/pubmed/26486062 http://dx.doi.org/10.4103/1008-682X.165948 |
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