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Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring

There is now strong evidence that the paternal contribution to offspring phenotype at fertilisation is more than just DNA. However, the identity and mechanisms of this nongenetic inheritance are poorly understood. One of the more important questions in this research area is: do changes in sperm DNA...

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Detalles Bibliográficos
Autores principales: Youngson, Neil A, Lecomte, Virginie, Maloney, Christopher A, Leung, Preston, Liu, Jia, Hesson, Luke B, Luciani, Fabio, Krause, Lutz, Morris, Margaret J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109891/
https://www.ncbi.nlm.nih.gov/pubmed/26608942
http://dx.doi.org/10.4103/1008-682X.163190