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Enhancing succinic acid biosynthesis in Escherichia coli by engineering its global transcription factor, catabolite repressor/activator (Cra)

This study was initiated to improve E. coli succinate production by engineering the E. coli global transcription factor, Cra (catabolite repressor/activator). Random mutagenesis libraries were generated through error-prone PCR of cra. After re-screening and mutation site integration, the best mutant...

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Detalles Bibliográficos
Autores principales:	Zhu, Li-Wen, Xia, Shi-Tao, Wei, Li-Na, Li, Hong-Mei, Yuan, Zhan-Peng, Tang, Ya-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109907/ https://www.ncbi.nlm.nih.gov/pubmed/27811970 http://dx.doi.org/10.1038/srep36526

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