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Probing the PI3K/Akt/mTor pathway using (31)P-NMR spectroscopy: routes to glycogen synthase kinase 3

Akt is an intracellular signalling pathway that serves as an essential link between cell surface receptors and cellular processes including proliferation, development and survival. The pathway has many downstream targets including glycogen synthase kinase3 which is a major regulatory kinase for cell...

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Detalles Bibliográficos
Autores principales: Phyu, Su M., Tseng, Chih-Chung, Fleming, Ian N., Smith, Tim A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109916/
https://www.ncbi.nlm.nih.gov/pubmed/27811956
http://dx.doi.org/10.1038/srep36544