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Potential biomarkers to follow the progression and treatment response of Huntington’s disease
Huntington’s disease (HD) is a rare genetic disease caused by expanded polyglutamine repeats in the huntingtin protein resulting in selective neuronal loss. Although genetic testing readily identifies those who will be affected, current pharmacological treatments do not prevent or slow down disease...
Autores principales: | Disatnik, Marie-Hélène, Joshi, Amit U., Saw, Nay L., Shamloo, Mehrdad, Leavitt, Blair R., Qi, Xin, Mochly-Rosen, Daria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110026/ https://www.ncbi.nlm.nih.gov/pubmed/27821553 http://dx.doi.org/10.1084/jem.20160776 |
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