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Access to a new class of synthetic building blocks via trifluoromethoxylation of pyridines and pyrimidines
Since the first synthesis of trifluoromethyl ethers in 1935, the trifluoromethoxy (OCF(3)) group has made a remarkable impact in medicinal, agrochemical, and materials science research. However, our inability to facilely incorporate the OCF(3) group into molecules, especially heteroaromatics, has li...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110255/ https://www.ncbi.nlm.nih.gov/pubmed/27857834 http://dx.doi.org/10.1039/c5sc02983j |