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Long Noncoding RNAs in Metabolic Syndrome Related Disorders

Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RN...

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Detalles Bibliográficos
Autores principales: Losko, Magdalena, Kotlinowski, Jerzy, Jura, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110871/
https://www.ncbi.nlm.nih.gov/pubmed/27881904
http://dx.doi.org/10.1155/2016/5365209
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author Losko, Magdalena
Kotlinowski, Jerzy
Jura, Jolanta
author_facet Losko, Magdalena
Kotlinowski, Jerzy
Jura, Jolanta
author_sort Losko, Magdalena
collection PubMed
description Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands.
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spelling pubmed-51108712016-11-23 Long Noncoding RNAs in Metabolic Syndrome Related Disorders Losko, Magdalena Kotlinowski, Jerzy Jura, Jolanta Mediators Inflamm Review Article Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands. Hindawi Publishing Corporation 2016 2016-11-02 /pmc/articles/PMC5110871/ /pubmed/27881904 http://dx.doi.org/10.1155/2016/5365209 Text en Copyright © 2016 Magdalena Losko et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Losko, Magdalena
Kotlinowski, Jerzy
Jura, Jolanta
Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_full Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_fullStr Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_full_unstemmed Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_short Long Noncoding RNAs in Metabolic Syndrome Related Disorders
title_sort long noncoding rnas in metabolic syndrome related disorders
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110871/
https://www.ncbi.nlm.nih.gov/pubmed/27881904
http://dx.doi.org/10.1155/2016/5365209
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