Cargando…
Long Noncoding RNAs in Metabolic Syndrome Related Disorders
Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RN...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110871/ https://www.ncbi.nlm.nih.gov/pubmed/27881904 http://dx.doi.org/10.1155/2016/5365209 |
_version_ | 1782467760119349248 |
---|---|
author | Losko, Magdalena Kotlinowski, Jerzy Jura, Jolanta |
author_facet | Losko, Magdalena Kotlinowski, Jerzy Jura, Jolanta |
author_sort | Losko, Magdalena |
collection | PubMed |
description | Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands. |
format | Online Article Text |
id | pubmed-5110871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-51108712016-11-23 Long Noncoding RNAs in Metabolic Syndrome Related Disorders Losko, Magdalena Kotlinowski, Jerzy Jura, Jolanta Mediators Inflamm Review Article Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands. Hindawi Publishing Corporation 2016 2016-11-02 /pmc/articles/PMC5110871/ /pubmed/27881904 http://dx.doi.org/10.1155/2016/5365209 Text en Copyright © 2016 Magdalena Losko et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Losko, Magdalena Kotlinowski, Jerzy Jura, Jolanta Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_full | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_fullStr | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_full_unstemmed | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_short | Long Noncoding RNAs in Metabolic Syndrome Related Disorders |
title_sort | long noncoding rnas in metabolic syndrome related disorders |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110871/ https://www.ncbi.nlm.nih.gov/pubmed/27881904 http://dx.doi.org/10.1155/2016/5365209 |
work_keys_str_mv | AT loskomagdalena longnoncodingrnasinmetabolicsyndromerelateddisorders AT kotlinowskijerzy longnoncodingrnasinmetabolicsyndromerelateddisorders AT jurajolanta longnoncodingrnasinmetabolicsyndromerelateddisorders |