Cargando…

Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography

Background. We tested the prevalence and impact of HCV seropositivity among Egyptian patients referred for coronary angiography. Subjects and Methods. This cross-sectional study was conducted in Zagazig University hospitals including 509 patients scheduled for elective coronary angiography between J...

Descripción completa

Detalles Bibliográficos
Autores principales: Salam, Ragab Abd El, Nabil, Baher, Saber, Marawan, AbdelWahab, Hany A., Saber, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110946/
https://www.ncbi.nlm.nih.gov/pubmed/27882261
http://dx.doi.org/10.1155/2016/1623197
_version_ 1782467775945506816
author Salam, Ragab Abd El
Nabil, Baher
Saber, Marawan
AbdelWahab, Hany A.
Saber, Tamer
author_facet Salam, Ragab Abd El
Nabil, Baher
Saber, Marawan
AbdelWahab, Hany A.
Saber, Tamer
author_sort Salam, Ragab Abd El
collection PubMed
description Background. We tested the prevalence and impact of HCV seropositivity among Egyptian patients referred for coronary angiography. Subjects and Methods. This cross-sectional study was conducted in Zagazig University hospitals including 509 patients scheduled for elective coronary angiography between June 2013 and June 2014. By taking full history on admission, laboratory workup including HCV Ab, echocardiography study, and coronary angiography, we calculated the mean number of coronary artery lesions and the mean number of affected coronary artery vessels for all patients. The severity of the coronary lesions was estimated using the Gensini score. Results. HCV seropositive patients referred for coronary angiography were about 30.3% (which is greater than the prevalence of HCV seropositivity among general population in Egypt), patients proved to have CAD who are HCV antibody positive had more severe coronary lesions than in seronegative one (p < 0.05), and patients proved to have CAD who are HCV antibody positive had comparable prevalence of cardiovascular risk factors as seronegative patients except for diabetes and hypertension which are more prevalent in seronegative patients (p < 0.05). Conclusion. Prevalence of HCV antibody positive patients referred for coronary angiography was about 30.3%, and CAD patients who are HCV antibody positive had more severe coronary lesions and less prevalence of diabetes and hypertension than HCV antibody negative.
format Online
Article
Text
id pubmed-5110946
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-51109462016-11-23 Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography Salam, Ragab Abd El Nabil, Baher Saber, Marawan AbdelWahab, Hany A. Saber, Tamer Cardiol Res Pract Research Article Background. We tested the prevalence and impact of HCV seropositivity among Egyptian patients referred for coronary angiography. Subjects and Methods. This cross-sectional study was conducted in Zagazig University hospitals including 509 patients scheduled for elective coronary angiography between June 2013 and June 2014. By taking full history on admission, laboratory workup including HCV Ab, echocardiography study, and coronary angiography, we calculated the mean number of coronary artery lesions and the mean number of affected coronary artery vessels for all patients. The severity of the coronary lesions was estimated using the Gensini score. Results. HCV seropositive patients referred for coronary angiography were about 30.3% (which is greater than the prevalence of HCV seropositivity among general population in Egypt), patients proved to have CAD who are HCV antibody positive had more severe coronary lesions than in seronegative one (p < 0.05), and patients proved to have CAD who are HCV antibody positive had comparable prevalence of cardiovascular risk factors as seronegative patients except for diabetes and hypertension which are more prevalent in seronegative patients (p < 0.05). Conclusion. Prevalence of HCV antibody positive patients referred for coronary angiography was about 30.3%, and CAD patients who are HCV antibody positive had more severe coronary lesions and less prevalence of diabetes and hypertension than HCV antibody negative. Hindawi Publishing Corporation 2016 2016-11-02 /pmc/articles/PMC5110946/ /pubmed/27882261 http://dx.doi.org/10.1155/2016/1623197 Text en Copyright © 2016 Ragab Abd El Salam et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Salam, Ragab Abd El
Nabil, Baher
Saber, Marawan
AbdelWahab, Hany A.
Saber, Tamer
Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography
title Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography
title_full Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography
title_fullStr Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography
title_full_unstemmed Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography
title_short Prevalence of Hepatitis C Virus Seropositivity and Its Impact on Coronary Artery Disease among Egyptian Patients Referred for Coronary Angiography
title_sort prevalence of hepatitis c virus seropositivity and its impact on coronary artery disease among egyptian patients referred for coronary angiography
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110946/
https://www.ncbi.nlm.nih.gov/pubmed/27882261
http://dx.doi.org/10.1155/2016/1623197
work_keys_str_mv AT salamragababdel prevalenceofhepatitiscvirusseropositivityanditsimpactoncoronaryarterydiseaseamongegyptianpatientsreferredforcoronaryangiography
AT nabilbaher prevalenceofhepatitiscvirusseropositivityanditsimpactoncoronaryarterydiseaseamongegyptianpatientsreferredforcoronaryangiography
AT sabermarawan prevalenceofhepatitiscvirusseropositivityanditsimpactoncoronaryarterydiseaseamongegyptianpatientsreferredforcoronaryangiography
AT abdelwahabhanya prevalenceofhepatitiscvirusseropositivityanditsimpactoncoronaryarterydiseaseamongegyptianpatientsreferredforcoronaryangiography
AT sabertamer prevalenceofhepatitiscvirusseropositivityanditsimpactoncoronaryarterydiseaseamongegyptianpatientsreferredforcoronaryangiography