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Investigating the effect of AS03 adjuvant on the plasma cell repertoire following pH1N1 influenza vaccination
Influenza pandemics require rapid deployment of effective vaccines for control. Adjuvants such as AS03 improve vaccine immunogenicity, but this mechanism is poorly understood. We used high-throughput B cell receptor sequencing of plasma cells produced following AS03-adjuvanted and non-adjuvanted 200...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110968/ https://www.ncbi.nlm.nih.gov/pubmed/27849037 http://dx.doi.org/10.1038/srep37229 |