Cargando…
Interaction of CCR4–NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis
Transcription factor EBF1 (early B-cell factor 1) regulates early B-cell differentiation by poising or activating lineage-specific genes and repressing genes associated with alternative cell fates. To identify proteins that regulate the diverse functions of EBF1, we used SILAC (stable isotope labeli...
Autores principales: | Yang, Cheng-Yuan, Ramamoorthy, Senthilkumar, Boller, Sören, Rosenbaum, Marc, Rodriguez Gil, Alfonso, Mittler, Gerhard, Imai, Yumiko, Kuba, Keiji, Grosschedl, Rudolf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110997/ https://www.ncbi.nlm.nih.gov/pubmed/27807034 http://dx.doi.org/10.1101/gad.285452.116 |
Ejemplares similares
-
Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming
por: Li, Rui, et al.
Publicado: (2018) -
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling
por: Bayer, Marc, et al.
Publicado: (2022) -
EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism
por: Ramamoorthy, Senthilkumar, et al.
Publicado: (2020) -
The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription
por: Rodríguez-Gil, Alfonso, et al.
Publicado: (2017) -
EBF1 is continuously required for stabilizing local chromatin accessibility in pro-B cells
por: Zolotarev, Nikolay, et al.
Publicado: (2022)