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Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes
We published a new method (BMC Bioinformatics 2014, 15:14) for searching for differentially expressed genes from two biological conditions datasets. The presentation of theorem 1 in this paper was incomplete. We received an anonymous comment about our publication that motivates the present work. Her...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111201/ https://www.ncbi.nlm.nih.gov/pubmed/27846811 http://dx.doi.org/10.1186/s12859-016-1322-0 |
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author | Dembélé, Doulaye Kastner, Philippe |
author_facet | Dembélé, Doulaye Kastner, Philippe |
author_sort | Dembélé, Doulaye |
collection | PubMed |
description | We published a new method (BMC Bioinformatics 2014, 15:14) for searching for differentially expressed genes from two biological conditions datasets. The presentation of theorem 1 in this paper was incomplete. We received an anonymous comment about our publication that motivates the present work. Here, we present a complementary result which is necessary from the theoretical point of view to demonstrate our theorem. We also show that this result has no negative impact on our conclusions obtained with synthetic and experimental microarrays datasets. |
format | Online Article Text |
id | pubmed-5111201 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-51112012016-11-21 Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes Dembélé, Doulaye Kastner, Philippe BMC Bioinformatics Correspondence We published a new method (BMC Bioinformatics 2014, 15:14) for searching for differentially expressed genes from two biological conditions datasets. The presentation of theorem 1 in this paper was incomplete. We received an anonymous comment about our publication that motivates the present work. Here, we present a complementary result which is necessary from the theoretical point of view to demonstrate our theorem. We also show that this result has no negative impact on our conclusions obtained with synthetic and experimental microarrays datasets. BioMed Central 2016-11-15 /pmc/articles/PMC5111201/ /pubmed/27846811 http://dx.doi.org/10.1186/s12859-016-1322-0 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Correspondence Dembélé, Doulaye Kastner, Philippe Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
title | Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
title_full | Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
title_fullStr | Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
title_full_unstemmed | Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
title_short | Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
title_sort | comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes |
topic | Correspondence |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111201/ https://www.ncbi.nlm.nih.gov/pubmed/27846811 http://dx.doi.org/10.1186/s12859-016-1322-0 |
work_keys_str_mv | AT dembeledoulaye commentsonfoldchangerankorderingstatisticsanewmethodfordetectingdifferentiallyexpressedgenes AT kastnerphilippe commentsonfoldchangerankorderingstatisticsanewmethodfordetectingdifferentiallyexpressedgenes |