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Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans

BACKGROUND: Local implantation of ex vivo concentrated, washed and filtrated human bone marrow-derived mononuclear cells (BMC) seeded onto β-tricalciumphosphate (TCP) significantly enhanced bone healing in a preclinical segmental defect model. Based on these results, we evaluated in a first clinical...

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Detalles Bibliográficos
Autores principales: Seebach, Caroline, Henrich, Dirk, Meier, Simon, Nau, Christoph, Bonig, Halvard, Marzi, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111224/
https://www.ncbi.nlm.nih.gov/pubmed/27846890
http://dx.doi.org/10.1186/s12967-016-1066-7

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