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Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans
BACKGROUND: Local implantation of ex vivo concentrated, washed and filtrated human bone marrow-derived mononuclear cells (BMC) seeded onto β-tricalciumphosphate (TCP) significantly enhanced bone healing in a preclinical segmental defect model. Based on these results, we evaluated in a first clinical...
Autores principales: | Seebach, Caroline, Henrich, Dirk, Meier, Simon, Nau, Christoph, Bonig, Halvard, Marzi, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111224/ https://www.ncbi.nlm.nih.gov/pubmed/27846890 http://dx.doi.org/10.1186/s12967-016-1066-7 |
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