Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

BACKGROUND: Individuals with 22q11.2 Deletion Syndrome (22q11.2 DS) are a specific high-risk group for developing schizophrenia (SZ), schizoaffective disorder (SAD) and autism spectrum disorders (ASD). Several genes in the deleted region have been implicated in the development of SZ, e.g., PRODH and...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Mingyan, Pedrosa, Erika, Hrabovsky, Anastasia, Chen, Jian, Puliafito, Benjamin R., Gilbert, Stephanie R., Zheng, Deyou, Lachman, Herbert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111260/
https://www.ncbi.nlm.nih.gov/pubmed/27846841
http://dx.doi.org/10.1186/s12918-016-0366-0

Ejemplares similares

Ejemplares similares