Genome editing: progress and challenges for medical applications

The development of the CRISPR-Cas platform for genome editing has greatly simplified the process of making targeted genetic modifications. Applications of genome editing are expected to have a substantial impact on human therapies through the development of better animal models, new target discovery...

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Detalles Bibliográficos
Autor principal: Carroll, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111268/
https://www.ncbi.nlm.nih.gov/pubmed/27846896
http://dx.doi.org/10.1186/s13073-016-0378-9
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author Carroll, Dana
author_facet Carroll, Dana
author_sort Carroll, Dana
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description The development of the CRISPR-Cas platform for genome editing has greatly simplified the process of making targeted genetic modifications. Applications of genome editing are expected to have a substantial impact on human therapies through the development of better animal models, new target discovery, and direct therapeutic intervention.
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spelling pubmed-51112682016-11-25 Genome editing: progress and challenges for medical applications Carroll, Dana Genome Med Comment The development of the CRISPR-Cas platform for genome editing has greatly simplified the process of making targeted genetic modifications. Applications of genome editing are expected to have a substantial impact on human therapies through the development of better animal models, new target discovery, and direct therapeutic intervention. BioMed Central 2016-11-15 /pmc/articles/PMC5111268/ /pubmed/27846896 http://dx.doi.org/10.1186/s13073-016-0378-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Carroll, Dana
Genome editing: progress and challenges for medical applications
title Genome editing: progress and challenges for medical applications
title_full Genome editing: progress and challenges for medical applications
title_fullStr Genome editing: progress and challenges for medical applications
title_full_unstemmed Genome editing: progress and challenges for medical applications
title_short Genome editing: progress and challenges for medical applications
title_sort genome editing: progress and challenges for medical applications
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111268/
https://www.ncbi.nlm.nih.gov/pubmed/27846896
http://dx.doi.org/10.1186/s13073-016-0378-9
work_keys_str_mv AT carrolldana genomeeditingprogressandchallengesformedicalapplications

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