Cargando…

The Mutation Profile of Calreticulin in Patients with Myeloproliferative Neoplasms and Acute Leukemia

OBJECTIVE: Calreticulin (CALR) plays important roles in cell proliferation, apoptosis, and immune responses. CALR mutations were described recently in Janus kinase 2 gene (JAK2)-negative or MPL-negative primary myelofibrosis (PMF) and essential thrombocythemia (ET) patients. CALR trails JAK2 as the...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jingyi, Hao, Jianguo, He, Na, Ji, Chunyan, Ma, Daoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111462/
https://www.ncbi.nlm.nih.gov/pubmed/26377485
http://dx.doi.org/10.4274/tjh.2015.0220