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Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP for clinical research

We previously reported that tumor vessel-redirected T cells, which were genetically engineered with chimeric antigen receptor (CAR) specific for vascular endothelial growth factor receptor 2 (VEGFR2), demonstrated significant antitumor effects in various murine solid tumor models. In the present stu...

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Detalles Bibliográficos
Autores principales:	Inoo, Kanako, Inagaki, Ryo, Fujiwara, Kento, Sasawatari, Shigemi, Kamigaki, Takashi, Nakagawa, Shinsaku, Okada, Naoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111575/ https://www.ncbi.nlm.nih.gov/pubmed/27909701 http://dx.doi.org/10.1038/mto.2016.24

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